Oxygen concentrations below 14% will not support the combustion of most fuels (and human exposure must be limited). Consideration of our comments and recommendations does not assure that no additional toxicity testing or research is needed on a halon replacement candidate to provide a complete assessment of the overall risks to human health. While several different types of halon have been developed since this product was first invented, many were dangerous or deadly to humans. Thirty-one workers were assessed, 22 who were present at the time of the discharge, and 9 who worked the next shift. This can cause people to suffocate. Since halon manufacturing was banned, a hunt has been on for something that works as well. Halon 1301 succeeded so well because it could be used in data centers, IT rooms, museums, libraries, surgical suites, and other locations where use of water-based suppressants could irreparably damage electronics or vital archival collections. The incident was complicated by a small Freon-22 leak several hours later. Inert gas agents are electrically non-conductive clean fire suppressants that are used in design concentrations of 35-50% by volume to reduce ambient oxygen concentration to between 14 and 10%. The strategy described is based on the experience and opinions of the authors. Human Inhalation of Halon 1301, HFC-134a and HFC-227ea for Collection of Pharmacokinetic Data 19 Aug 97 Document Abstract: International agreement and regulatory decisions have driven activities to replace ozone depleting chemicals (ODCs) in fire and House, R.A.}, abstractNote = {An accidental discharge of a Halon 1301 system is reported. Halon 1211 also has low toxicity, although it is more toxic than Halon 1301, and thus considered unsuitable for flooding systems. @article{osti_7013389, title = {Health effects of Halon 1301 exposure}, author = {Holness, D.L. Halon gas is a chemical compound that is often used in fire suppression systems. **Interruption of the Central Nervous System** Large amounts of halon gas that are inhaled can interfere with the proper function of the central nervous system. Damage from inhaling gas fumes may happen accidentally, but many cases result from people looking for a quick “high.” Intoxicating effects may last only a few minutes and many users repeatedly inhale gas fumes for an extended effect, leading to life-threatening situations. (Experimental animals have also been exposed to 2% concentrations of Halon 1301 for 30 hours per week for 4 months, with no discernible health effects.) risk to human health. High concentrations of halon can create an oxygen-deficient environment. Halon's Role in Stratospheric Ozone Depletion The Halon covered by EPA Rule 40 CFR Part 82, Subpart H contains the chemical element bromine (Br) and also, in the case of Halon 1211 specifically, chlorine (Cl).Br and Cl both contribute to stratospheric ozone destruction.

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